Disease: Fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846